Apoptosis regulation and execution signaling pathways
In this section you will learn more about the key processes that control apoptosis, as well as the enzymatic cascade that is responsible for the destruction of cellular proteins and which underpins the apoptotic method of cell destruction.
- Signaling pathways to apoptosis. Learn more about the key pathways involved in the control and execution of apoptosis.
- Caspase cascade. Discover the members of the caspase family of proteolytic enzymes that are responsible for amplifying the pro-apoptotic signal and implementing cell destruction.
- Intrinsic pathway. Discover how the intrinsic signaling pathway is activated and the key components that transfer the signal to the caspase cascade and ultimately cell destruction.
- Extrinsic pathway. Learn about the extrinsic pathway and how it converges with the intrinsic signaling pathway at the level of the caspase cascade.
- Oncogenes, tumor suppressors, and apoptosis in cancer. Read about the genes that suppress the formation of tumors, as well as the oncogenes that drive proliferation of cancer cells and how these relate to the components of the apoptotic pathways.